Novasep is a leading provider of integrated manufacturing solutions for the Life Science industries offering a wide range of flexible assets, specialized technologies and advanced process capabilities for the synthesis and purification of APIs and HPAPIs. We provide unique services for the development and cGMP manufacture of antibody-drug conjugates including the payload, the linker and the monoclonal antibody.
Quanta BioDesign was founded for the purpose of developing a line of products involved in drug discovery and diagnostic development. For 30 years the PEGylation of biologics has been completely defined by the use of generally high MW and highly polydispersed PEGs. While showing promising results in the clinic, it has serious limitations in control and characterization. Our single molecular weight ethylene glycol conjugation technology, dPEG, can eliminate common problems found in the development of diagnostic and therapeutic products.
A Bavarian based company that offers a wide selection of payloads for ADCs. We provide state of the art molecules as well as contract manufactured payloads derived from fermentation, fungi, soil, algae or chemically synthesized. Non GMP for R&D to cGMP for APIs.
MicroBiopharm Japan has been manufacturing high-potent compounds by fermentation technique for a long time. These natural compounds and their derivatives are used as anticancer drugs usually. In addition, they could also be used as payloads in the field of ADC such as DM-1 (Ansamitocin P3 derivative), Doxorubicin, Alpha-amanitin, Camptotecin analogues, and so on. MicroBiopharm Japan supports development of ADC drugs by supply of these payloads and their linker conjugates at a competitive price and high quality.
NOF Corporation is the leading commercial supplier of activated PEG products and is providing site-specific linkers, such as, linear and branched hetero-activated PEG, and single molecular weight PEGs for the development of next generation Antibody-Drug Conjugates. NOF also supplies ultra-pure polysorbates 20 and 80 for stabilizing the formulation of antibody and protein… Read More.
More info to follow.
CARBOGEN AMCIS combines world-class chemistry skills to provide seamless drug development and commercialization services for leading pharmaceutical and biotechnology companies. Through our customised offering we provide an array of integrated services to support the fast supply of complex Antibody Drug Conjugates (ADCs). Our infrastructure is fully GMP compliant and includes a workshop dedicated to ADCs in Switzerland and a formulation site with lyophilization capabilities in France.
Genovis provides unique enzymes suitable for development and characterization of ADCs, mAbs, proteins, Fc-fusion proteins and biosimilars. The SmartEnzymes™ portfolio consists of:
- FabRICATOR® (IdeS), FabRICATOR®Z (IdeZ), FabULOUS® (SpeB) and GingisKHAN™ (Kgp). These enzymes are for preparation of subunits for further analysis using LC and MS.
- IgGZERO® (EndoS) and GlycINAT… Read More.
Pierre FABRE CDMO proposes its international partners a full service, from clinical development to commercial production in the following fields of expertises: manufacturing of APIs, supercritical CO2 formulation, production of pharmaceutical lozenges and fill & finish of injectable products (vials, prefilled syringes), including conventional cytotoxic and biotechnology products… Read More.