Genovis provides unique enzymes suitable for development and characterization of ADCs, mAbs, proteins, Fc-fusion proteins and biosimilars. The SmartEnzymes™ portfolio consists of:
- FabRICATOR® (IdeS), FabRICATOR®Z (IdeZ), FabULOUS® (SpeB) and GingisKHAN™ (Kgp). These enzymes are for preparation of subunits for further analysis using LC and MS.
- IgGZERO® (EndoS) and GlycINAT… Read More.
At Levena BioPharma, we interface complex synthetic chemistry with antibody research providing our clients with the latest technologies and comprehensive services to advance ADC projects from discovery to IND. Our ADC platform encompasses: ADC screening tools; bioactive molecules (toxins) for research and in cGMP grade; optimized linker-toxins; conjugation services; ADC toxicity screening; and ADC optimization & processing.
Morphotek®is a biotechnology company focused on the development of antibody-based therapies. In oncology, we are developing biological therapies that target underlying disease pathways and can overcome the immunosuppressive effects by tumors on immune-mediated experimental therapies. As part of this approach, we have developed proprietary ADC technologies that utilize REsidue-SPEcific Conjugation Technology™ (RESPECT™) and proprietary payloads to develop ADCs to internal and clients’ strategic targets through our end-to-end ADC Services
NOF Corporation is the leading commercial supplier of activated PEG products and is providing site-specific linkers, such as, linear and branched hetero-activated PEG, and single molecular weight PEGs for the development of next generation Antibody-Drug Conjugates. NOF also supplies ultra-pure polysorbates 20 and 80 for stabilizing the formulation of antibody and protein… Read More.
Piramal Pharma Solution’s Antibody Drug Conjugate Business is one of the world’s leading contract development and manufacturing sites delivering early and late phase clinical and commercial supplies. Our flexible manufacturing regime and dedication to ADC processing is why our clients choose Piramal as their preferred partner. We seek to reduce the complexity associated with ADC processing allowing for integrated and seamless scale-up of each unique ADC program, including fill finish.
At ProteinSimple, we’re changing the way scientists analyze proteins. Our innovative product portfolio helps researchers reveal new insight into proteins, advancing their understanding of protein function. We enable cutting-edge research to uncover the role of proteins in disease and provide novel approaches to develop and analyze protein-based therapeutics. We empower you to make your next discovery by eliminating common protein analysis workflow challenges. ProteinSimple is part of the Protein Platforms division of Bio-Techne.
Formed in 2016, PROVEO™ is a four-company CMO alliance providing seamless, end-to-end solutions for the process development and cGMP manufacture of ADCs. Combining integrated project management, logistics, supply chain, and production—the PROVEO Alliance blends decades of industry experience and competencies with proven capabilities and the very latest in technological innovation to deliver an unmatched quality, dependability, and… Read More.
Quanta BioDesign was founded for the purpose of developing a line of products involved in drug discovery and diagnostic development. For 30 years the PEGylation of biologics has been completely defined by the use of generally high MW and highly polydispersed PEGs. While showing promising results in the clinic, it has serious limitations in control and characterization. Our single molecular weight ethylene glycol conjugation technology, dPEG, can eliminate common problems found in the development of diagnostic and therapeutic products.
SafeBridge Consultants, Inc. is the premier resource for high-level safety, health and environmental support to the pharmaceutical and biotechnology industry. Comprised of industry leaders in toxicology, analytical chemistry and industrial hygiene… Read More