NextGen CAB-ADCs: Maximizing Safety & the Therapeutic Index
Time: 1:30 pm
day: Track B - Pre-Conf- PM
Details:
- Overviewing the CAB platform to minimize antigen related toxicity by pH-selective binding in the tumor microenvironment
- Optimizing linker selection for improved serum stability and tumor-targeted payload release
- Discussing approaches to maximize the therapeutic index of ADCs