Ben-Quan Shen

Ben-Quan Shen

Company: Genentech

Job title: Principal Scientist


Interaction of ADC Drug Payload with Plasma Protein May Impact the PK & Tumor Distribution: A Case Study with Anti-Ly6E-seco-dimer ADC 11:30 am

• Providing a general discussion on the key factors impacting ADC development • Presenting a case study to show the adduct formation of anti- Ly6E ADC with seco-CBI dimer with A1M led to a decrease in systemic clearance and attenuated tumor distribution • Highlighting the importance of selecting an appropriate linkerdrug for ADC development, and…Read more

day: day 2 track 2

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