Ruud Coumans

Ruud Coumans

Company: Byondis

Job title: Project Leader Antibody-Drug Conjugates

Seminars:

ByonShieLD® – A Platform for the Generation of Site-Specific Antibody– Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines 12:00 pm

• Identifying optimal sites for conjugating a hydrophobic payload through use of an in silico screening procedure • Compared to randomly conjugated ADCs, the sitespecific ADCs were less hydrophobic and had better efficacy and exposure in an in vivo xenograft model • Discussing how site-specific ADCs can be manufactured using a newly discovered selective reducing…Read more

day: day 1 track 1 am

© Copyright 2022 Hanson Wade | Design and site by Event Engine | Hanson Wade Limited is registered in England & Wales, number 06752216.
Registered Office: Suite A, 6 Honduras Street, London EC1Y 0TH.