The Global Premier Conference for End-to-End ADC Innovation & Success
With the boom in ADC activity and the ever-expanding therapeutic landscape, much of the current clinical activity centers around select payload mechanisms, with TOPO1 and MMAE payloads accounting for over 70% of all clinical-stage ADCs. The 2025 ADC target space tells a similar story, with clinical development biased towards validated targets HER2, TROP2 and EGFR.
With questions being raised on how many ADCs in crowded payload MoA and target landscapes will lead to significant patient impact, the need for ADC innovation has never been more important.
As the world’s definitive and longest-standing antibody-drug conjugate forum, the 16th World ADC San Diego is committed to spotlighting the trailblazing innovation pushing ADCs to earlier-line oncology treatments. Showcasing differentiation across the entire ADC value chain, the 2025 program is built to ensure future ADCs provide a meaningful impact to oncology patients in need.

End-to-End Content to Suit Your Team's Needs
Whether you are brand new to the field or have over a decade of experience, work in discovery or manufacturing, hold a strategic position or work day-to-day in the lab, World ADC San Diego offers something for you with exclusive industry-led content spanning:

Track 1:
Discovery Chemistry

Track 2:
Discovery Biology

Track 3:
Preclinical

Track 4:
Translational Medicine

Track 5:
Clinical Lessons

Track 6:
Process & Analytical Development

Track 7:
Manufacturing & Supply Chain
More Than a Meeting: Celebrate the World ADC Experience
As the ADC community reunites at the week to fully immerse yourself in all things antibody drug conjugate, make sure you take part and enjoy the variety of structured networking opportunities beyond the scientific presentations, including:

Ambassador's Reception

Pre-Event Partnering Platform

Scientific Poster Sessions

Drinks Reception

Exhibition Booths

12th World ADC Awards
Brand New Presenting Companies for 2025
Alongside 170+ industry-leading speakers on the 2025 faculty, this year we are proud to spotlight new clinical stage companies presenting their ADC therapeutic innovation for the first time:






Plan Your 4-Day World ADC San Diego Trip
Below is a snapshot of what you can expect over the four days of cutting-edge content to help you plan your time effectively. If you have any questions, please get in touch.
Seminar Day - Monday, November 3
Spanning innovation and strategy across novel conjugates, toxicity, combination therapies, bioanalytics and CMC, the seminar day is designed to showcase the most important ADC bottlenecks and areas of innovation led by forward-thinking ADC experts.
Introduction to ADCs Day
Learn the ADC discovery and development fundamentals
3rd Novel Conjugates Day
Stay ahead of the ADC payload and targeting moiety design curve
2nd Pharmacology Day
Discover next-generation ADC MoA and tumor-targeting behavior
6th Toxicity Day
Identify, characterize and mitigate on and off-target ADC toxicities
9th ADCs in Combinations Day
Smartly select ADC combination partners to tackle patient resistance
NEW: 1st PK/PD & Bioanalytical Day
Leverage bioanalytical technologies to characterize ADC PK/PD in humans
NEW: 1st Analytical & CQA Day
Identify and meet CQAs to maximize ADC product quality and process control
7th CMC Day
Elevate ADC scale-up and manufacturing whilst meeting regulatory expectations
Scientific Program Days - Tuesday November 4 & Wednesday November 5
Headlined with keynote plenary sessions led by senior ADC leaders showcasing blockbuster development and differentiation driving ADCs to standard-of-care treatments, the main scientific program days will unveil cutting-edge, end-end ADC development insights through data-driven presentations from pioneering companies in the community across seven content tracks:
- Discovery Chemistry
- Discovery Biology
- NEW! Preclinical
- NEW! Translational Medicine
- Clinical Lessons
- Process & Analytical Development
- Manufacturing & Supply Chain
Throughout both days, you can access structured networking opportunities to reconnect with your peers and meet fresh faces to make new scientific and business “linkers” as the ADC community reunites all under one roof.
After the scientific presentations, make sure you don’t miss the popular Evening Drinks Reception and 12th World ADC Awards at the end of each day.
Workshop Day - Thursday, November 6
Reignited with the new insights from the main conference days, continue the conversation with like-minded peers in a series of discussions, debates, and forward-thinking sessions to find solutions to your most pressing challenges in the ADC field.
Taking place in more intimate settings, make sure to bring your own questions to these extended, collaborative sessions with content tailored for beginners in the field and for everyone working on ADCs.
Pick one morning and one afternoon workshop, out of:
- Deep-diving into ADC chemistry & conjugation to understand the fundamentals behind next-generation ADC properties & design
- ADC target 101: Keeping up to date with cutting-edge anti-tumor target discovery & validation
- Assessing translational challenges & opportunities to increase predictability of ADCs, bispecific ADCs & combination therapies
- Connecting ADC design to performance: How is each component contributing to ADC clinical safety & efficacy?
- Discussing control strategy, purge factors & regulatory findings for ADCs
- Delving into strategy & stakeholder management to optimize ADC outsourcing & supply chain