Jay Harper

Director, Oncology Targeted Discovery AstraZeneca

Seminars

Monday 3rd November 2025
Chair:

In an ever-growing clinical landscape and with the threat of patient resistance, the role of combinations is crucial to bring better ADC treatments to oncology patients.

Join this long-standing seminar day for an overview of ADC clinical combination leaders, assess applications of dual payload ADCs to tackle payload resistance, and delve into rationale-driven practices to smartly select and investigate the right ADC combination partners

Download the Full Event Guide for full details

Monday 3rd November 2025
Assessing the Benefits & Challenges of ADC Combinations & Exploring Future Directions
2:00 pm

Rejoin your ADC combination speakers and attendees after lunch for a closing panel discussion to discuss, debate and evaluate the opportunities and challenges in combination clinical performance, optimising partner selection, the

power of ADC sequencing and dual payload conjugates, and more. Make sure to come with your thoughts and questions prepared!

Discussion Highlights Include:

  • Explore the impact of ADC combination on the oncology treatment landscape: Will combination therapies become the norm as ADCs progress to earlier-line patient therapies?
  • Understanding the best rationale to smartly select appropriate ADC combination partners
  • Evaluating the ability of ADC sequencing and dual payload combinations to combat resistance to payloads
Monday 3rd November 2025
ADC Combinations: Understanding Rationale, Clinical Highlights & Future Therapeutic Opportunities
10:30 am
  • Optimizing strategy for ADC combination trials
  • Overviewing exciting ADC combination data generated in 2025
  • Looking to the future: what are the next steps for progressing ADC combinations?

Jay Harper - 16th World ADC San Diego