Nicolas Camper
Vice President - ADCs & Bioconjugates Abzena
Seminars
Tuesday 4th November 2025
Streamlining Innovation in ADC Design Through Manufacturing with ThioBridge™ Conjugation & Linker Technology
11:30 am
- Delving into mechanistic insights of ThioBridge™ and its advantages over conventional stochastic conjugation approaches, demonstrated through in vitro and in vivo ADC stability data
- Exploring how DAR can be precisely controlled using ThioBridge™ to optimize ADC therapeutic activity
- Assessing design strategies for optimizing linker-payload combinations to improve in vivo efficacy, supported by relevant preclinical data
- Manufacturing Considerations: Understanding key aspects of ThioBridge™ linker-payload and ADC manufacturing processes
