Prathap Kumar Mahalingaiah
Senior Director, Oncology Safety AstraZeneca
Seminars
Monday 3rd November 2025
Discovery Safety Strategy for ADCs: Navigating Opportunities & Challenges in the Application of Human In Vitro Models
3:00 pm
- Laying out discovery safety strategy for ADCs
- Applying advanced in vitro models to complement ADC safety strategy alongside in vivo preclinical models to prioritize and select the safest ADC molecules
- Integrating bioanalytical methods and QST approaches with in vitro toxicity data to improve early-stage clinical toxicity predictions
