Assessing Immunogenic Senescence to Promote the Activity of Topo1 Inhibitor ADCs - 17th World ADC San Diego

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Assessing Immunogenic Senescence to Promote the Activity of Topo1 Inhibitor ADCs

2:30 pm - Monday 12th October 2026

Exploring how Topo1 and Topo1- ADCs elicit immunogenic cell stress in vivo through the induction of cellular senescence
Delineating the host immune cell requirements for Topo1-induced immunogenicity
Identifying biomarkers of immunogenic cell stress mediated by Topo1 ADCs

Speakers:

Doug Kline

Doug Kline

Senior Scientist II

Abbvie