Bridging Preclinical Models & Clinical Success: Leveraging PDOs & RWD to Advance ADC Development

  • Applying RWD to identify novel therapeutic targets and provide insights into ADC development with responder populations
  • Examining how patient-derived organoids can enhance biomarker validation and help guide therapeutic decisions
  • Highlighting a “lab-in-theloop” approach to incorporate screening panels of PDOs, optimized for ADC evaluation, and RWD to enhance biomarker validation and guide pipeline prioritization