Developing a Radionuclide TLR-7 Immunostimulatory Dual Payload ADC to Achieve In Situ Anti-Tumor Vaccination Response

• Describing dual payload ADC conjugation strategy and physicochemical properties to demonstrate co-delivery therapeutic benefit versus single payload therapies
• Exploring biodistribution data and in-human dosimetry calculations to predict safe radiation exposure
• Evaluating immunological and imaging studies to achieve in situ vaccination response

Speakers:

Labros Meimetis

Assistant Research Professor

University of Wisconsin, School of Medicine & Public Health