Developing Site-Specific Dual Payload ADCs Featuring Novel Linker Payloads to Overcome Resistance Mechanisms

  • Leveraging a cutting-edge cell-free system to develop novel dual payload ADCs
  • Showcasing the synergetic efficacy of Top1i combined with diverse MoA payloads to overcome the resistance
  • Enhancing preclinical efficacy in both in vitro and in vivo models with dual payload ADCs