Discovery Safety Strategy for ADCs: Navigating Opportunities & Challenges in the Application of Human In Vitro Models
- Laying out discovery safety strategy for ADCs
- Applying advanced in vitro models to complement ADC safety strategy alongside in vivo preclinical models to prioritize and select the safest ADC molecules
- Integrating bioanalytical methods and QST approaches with in vitro toxicity data to improve early-stage clinical toxicity predictions