Cen (Cathy) Guo
Director - Clinical Pharmacology Pfizer
Seminars
Thursday 6th November 2025
Workshop highlights include:
- Breaking down case studies of progressing ADC development across Phase I-III clinical trails
- Delving into exposure response modeling and analysis to inform ADC dosing and clinical activity
- Finding the right patient for the right ADC: evaluating when and how to implement patient cut-off criteriaÂ
Wednesday 5th November 2025
Breaking Down Strategy & Unique Considerations to Set Up ADC Dose Escalation for Success
11:30 am
- Setting up first-in-patient dose escalation study for ADCs (starting dose and dose regimen selection, dose escalation increment, bioanalytical assays)
- Applying modeling and simulation tools in first-inpatient study for ADCs
- Selecting optimal ADC dose for expansion
