Greg Thurber
Associate Professor, Chemical & Biomedical Engineering University of Michigan
Seminars
Thursday 6th November 2025
Workshop highlights include:
- Exploring the multiscale mechanisms of ADC distribution, from subcellular to cellular, tissue, organ, and systemic biodistribution
- Discussing the (sometimes) counterintuitive results of ADC efficacy in animals and the clinic
- Reviewing the practical implementation of an ADC simulator to predict how ADC design impacts efficacy
Tuesday 4th November 2025
Contextualizing Learnings From Translational Profiles of Approved ADCs to Unlock Best Approaches to Preclinical Dosing in Mouse Models
3:00 pm
- Exploring the pattern of preclinical dosing in mouse models to clinical profiles from approved ADCs
- Explaining how to best approach dosing and efficacy in mouse models to avoid overdosing and set up translation for success
- Utilizing PDX and computational models to understand patient responses in situations with multiple approved ADC options
