Greg Thurber
Associate Professor, Chemical & Biomedical Engineering University of Michigan
Seminars
Thursday 6th November 2025
Workshop highlights include:
- Exploring the multiscale mechanisms of ADC distribution, from subcellular to cellular, tissue, organ, and systemic biodistribution
- Discussing the (sometimes) counterintuitive results of ADC efficacy in animals and the clinic
- Reviewing the practical implementation of an ADC simulator to predict how ADC design impacts efficacy
Wednesday 5th November 2025
Presentation Sneak Peek:
Contextualizing Learnings From Translational Profiles of Approved ADCs to Unlock Best Approaches to Preclinical Dosing in Mouse Models
- Exploring the pattern of preclinical dosing in mouse models to clinical profiles from approved ADCs
- Explaining how to best approach dosing and efficacy in mouse models to avoid overdosing and set up translation for success
- Utilizing PDX and computational models to understand patient responses in situations with multiple approved ADC options
Wednesday 5th November 2025
Presentation Sneak Peek:
Contextualizing Learnings From Translational Profiles of Approved ADCs to Unlock Best Approaches to Preclinical Dosing in Mouse Models
- Exploring the pattern of preclinical dosing in mouse models to clinical profiles from approved ADCs
- Explaining how to best approach dosing and efficacy in mouse models to avoid overdosing and set up translation for success
- Utilizing PDX and computational models to understand patient responses in situations with multiple approved ADC options
