Greg Thurber

Associate Professor, Chemical & Biomedical Engineering University of Michigan

Seminars

Thursday 6th November 2025
Workshop highlights include:
  • Exploring the multiscale mechanisms of ADC distribution, from subcellular to cellular, tissue, organ, and systemic biodistribution
  • Discussing the (sometimes) counterintuitive results of ADC efficacy in animals and the clinic
  • Reviewing the practical implementation of an ADC simulator to predict how ADC design impacts efficacy

Wednesday 5th November 2025
Presentation Sneak Peek:

Contextualizing Learnings From Translational Profiles of Approved ADCs to Unlock Best Approaches to Preclinical Dosing in Mouse Models

  • Exploring the pattern of preclinical dosing in mouse models to clinical profiles from approved ADCs
  • Explaining how to best approach dosing and efficacy in mouse models to avoid overdosing and set up translation for success
  • Utilizing PDX and computational models to understand patient responses in situations with multiple approved ADC options

Wednesday 5th November 2025
Presentation Sneak Peek:

Contextualizing Learnings From Translational Profiles of Approved ADCs to Unlock Best Approaches to Preclinical Dosing in Mouse Models

  • Exploring the pattern of preclinical dosing in mouse models to clinical profiles from approved ADCs
  • Explaining how to best approach dosing and efficacy in mouse models to avoid overdosing and set up translation for success
  • Utilizing PDX and computational models to understand patient responses in situations with multiple approved ADC options
Greg Thurber - 16th World ADC San Diego