Gregory Sacha
Senior Scientist Simtra BioPharma Solutions
Seminars
Tuesday 13th October 2026
Navigating Formulation Development for an ADC: Solution Vs. Lyophilization
3:30 pm
- Contextualizing ADC and large molecule sensitivity to justify studying variables in a solution environment ahead of more complicated freezing and drying environments
- Undergoing detailed evaluation of a molecule in solution state to help determine suitability for solution formulation versus freeze-drying
- Evaluating study findings to demonstrate how a dual approach to formulation development can speed the decision to formulate a molecule as a solution or a freeze-dried solid based on in-process data
