Ha Le
Senior Scientist, Biologics Analytical R&D Merck & Co
Ha Le is a Senior Scientist in Biologics Analytical R&D at Merck, where she supports analytical development through expertise in protein characterization, biophysical methods, and complex assay execution. Her background spans hard to express proteins, chromatography, LC MS proteomics, SPR, BLI, and biochemical assays, reflecting a strong foundation in therapeutic development. Originally from Vietnam, Ha brings cross cultural perspective, a passion for mentoring, and a commitment to scientific excellence shaped through her biochemistry research training at the University of Delaware.
Seminars
Wednesday 14th October 2026
Evaluating Environmental Temperature as a Hidden Critical Factor in icIEF for a Late-Stage ADC
3:00 pm
- Explaining how method validation failures revealed environmental temperature as an overlooked driver of icIEF performance during method development
- Small increases in ambient temperature disrupt separation, impacting ADC charge variant profiling and data reliability
- Defining a controlled temperature window to enable robust, transferable icIEF performance across sites and instruments for a late-stage ADC
