HSING-MAO CHU
Chief Executive Officer T-E Meds
Seminars
Monday 12th October 2026
Developing Efficacious, Stable & Safe High-DAR Mono & Dual Payload ADCs via Modular Multi-Arm Drug Bundle Technology & Flexible Conjugation
10:30 am
- Exploring stabilized linker designs and optimized dual payload combinations to enhance ADC stability, efficacy, and overcome drug resistance
- Assessing flexible conjugation methods through thiol maleimide and copper free click chemistries to allow precise drug bundle attachment and optimal DAR
- Explaining how site-specific conjugation of drug bundles enables high-DAR mono and dual payload ADCs with superior efficacy, stability and safety
