Huifang Dong
Head, LMP Porton Chemicals
Seminars
Monday 12th October 2026
Spotlighting Challenges & Strategies for XDC Novel Conjugates (Dual Payload ADC & AOC) & Analytical Characterization
12:30 pm
- Comparing conjugation designs for dual payload ADCs and AOCs, including single-site, dual-site, random, and site-specific approaches
- Addressing early development challenges in hydrophobicity, conjugation precision, aggregation, and process control through linker design, reaction optimization, and purification
- Reviewing supporting analytical characterization and integrated CRDMO capabilities for advancing XDC programs toward GMP manufacturing
