Jay Mettetal

Senior Director, Oncology Bioscience AstraZeneca

Seminars

Monday 3rd November 2025
Evaluating Mechanisms of ADC Drug Resistance & Strategies of Rational & Orthogonal Combinations to Improve Outcomes
1:30 pm
  • Understanding the role of antigen and payload-mediated resistance mechanisms
  • Laying out considerations of how cellular heterogeneity can contribute to ADC resistance
  • Exploring examples of how mechanistic and orthogonal combinations can be applied towards improving ADC activity
Jay Mettetal - 16th World ADC San Diego