Jean-Francois Martini
Senior Director, Translational Strategy & Applications Guardant Health
Seminars
Wednesday 14th October 2026
Beyond Tumor Tissue ADC Trials: Exploring ctDNA Dynamics & Multiomic Approaches for Faster Development Decisions
11:30 am
- Understanding how ctDNA dynamics can provide an early, quantitative molecular response readout to inform program ADC Go/No-Go decisions and dose or cohort expansion selection
- Learning how ctDNA can inform response assessment when imaging is uninformative or unavailable
- Seeing how multiomic approaches and epigenomic signatures in blood can be used to assign tumor subtype and identify subtype transformation
