Jeffrey Settleman

Senior Vice President, Chief Scientific Officer, Oncology R&D Pfizer

Dr. Jeff Settleman is the Chief Scientific Officer for the Oncology Research Unit and serves as the La Jolla site head, leading all oncology research at our two major Research hubs in La Jolla, CA and Bothell, WA.

Jeff is an internationally recognized expert in molecularly targeted cancer therapeutics, cancer drug resistance, and personalized cancer medicine. Jeff held numerous notable positions in both academia and industry before joining the Pfizer team. Prior to his current role, he served as Head of Oncology Research at Calico Life Sciences and led Discovery Oncology at Genentech.

Seminars

Tuesday 4th November 2025
Panelists:
  • Evaluating the landscape of ADC therapies: is the risk of innovation now lower than the risk of irrelevancy?
  • Assessing hurdles and opportunities to achieve differentiated ADC profiles in crowded ADC payload and target fields
  • Delving into novel ADC payloads: what new MoAs are emerging and what has been demonstrated so far?
  • Understanding perspectives on the future of ADC development across ADC design, targeting, and precision medicine approaches
Jeffrey Settleman - 16th World ADC San Diego