Krishna Bajjuri
Executive Director, ADC Chemistry & Discovery Sutro Biopharma
Krishna Bajjuri is Senior Director of ADC Discovery, Chemistry at Sutro Biopharma, where he leads efforts to advance next-generation single and multi-payload ADCs. He is a highly accomplished R&D leader and drug discovery team leader with over 16 years of experience in the discovery and development of ADCs, small molecules, cytotoxic payloads, innate immune agonists, linkers, and linker payload systems for ADCs, dpADC, iADCs, and cytokine-based therapeutics. He has over a decade of experience at Sutro Biopharma and a strong track record of advancing multiple ADCs, dpADCs & cytokine derivatives into clinical trials
Seminars
- Leveraging a cutting-edge cell free platform and novel payload classes to discover high-DAR dual payload ADCs aimed at overcoming resistance to single payload ADCs
- Demonstrating synergistic efficacy of Topo1-based combinations with diverse mechanisms, including DDR inhibitors, to enhance anti-tumor activity
- Validating improved preclinical efficacy of dual payload ADCs across in vitro and in vivo/PDX models to support their potential in resistant tumor settings
Rejoin the Discovery Chemistry speakers for a closing panel discussion to break down the key learnings and future directions in ADC chemistry and MoA innovation. Listen and engage with your fellow attendees as they discuss showing promise within novel cytotoxic, non-cytotoxic and dual payload ADCs, and what still needs to be proven to unlock differentiation to combat patient resistance.
