Krishna Bajjuri
Sr Director Sutro Biopharma
Seminars
Wednesday 14th October 2026
Summary Panel Discussion: What is Showing the Most Promise & What Still Needs to be Proven in ADC Chemistry & Mechanistic Innovation?
2:30 pm
Rejoin the Discovery Chemistry speakers for a closing panel discussion to break down the key learnings and future directions in ADC chemistry and MoA innovation. Listen and engage with your fellow attendees as they discuss showing promise within novel cytotoxic, non-cytotoxic and dual payload ADCs, and what still needs to be proven to unlock differentiation to combat patient resistance.
Wednesday 14th October 2026
Leveraging Novel Payload MoAs & Combinations to Differentiate ADC Mechanisms & Combat Patient Resistance
Monday 12th October 2026
Exploring Next-Generation High DAR Dual Payload ADCs Featuring Novel Payloads to Enhance Efficacy, Overcome Resistance & Improve Safety
12:30 pm
- Leveraging a cutting-edge cell free platform and novel payload classes to discover high-DAR dual payload ADCs aimed at overcoming resistance to single payload ADCs
- Demonstrating synergistic efficacy of Topo1-based combinations with diverse mechanisms, including DDR inhibitors, to enhance anti-tumor activity
- Validating improved preclinical efficacy of dual payload ADCs across in vitro and in vivo/PDX models to support their potential in resistant tumor settings
