Krishna Bajjuri
Executive Director, ADC Chemistry & Discovery Sutro Biopharma
Krishna Bajjuri is Senior Director of ADC Discovery, Chemistry at Sutro Biopharma, where he leads efforts to advance next-generation single and multi-payload ADCs. He is a highly accomplished R&D leader and drug discovery team leader with over 16 years of experience in the discovery and development of ADCs, small molecules, cytotoxic payloads, innate immune agonists, linkers, and linker payload systems for ADCs, dpADC, iADCs, and cytokine-based therapeutics. He has over a decade of experience at Sutro Biopharma and a strong track record of advancing multiple ADCs, dpADCs & cytokine derivatives into clinical trials
Seminars
Monday 12th October 2026
Exploring Next-Generation High DAR TOPO1i x DDRi Dual Payload ADCs to Improve Efficacy, Overcome Resistance & Enhance Safety
12:30 pm
- Leveraging Sutro’s cell-free expression and site-specific technologies to develop homogeneous, high-DAR TOPO1i × DDRi dual payload ADCs
- Demonstrating synergistic activity of TOPO1i with proprietary DDR inhibitors, including PARPi and ATRi to overcome DNA repair and drug efflux mediated resistance
- Demonstrating superior preclinical efficacy of TOPO1i × DDRi dpADCs compared with single payload ADCs
Tuesday 13th October 2026
Leveraging Novel Payload MoAs & Combinations to Differentiate ADC Mechanisms & Combat Patient Resistance
