Nicholas Willumsen
Director & Head of Oncology Nordic Bioscience A/S
Seminars
Tuesday 4th November 2025
Leveraging Tumor Fibrosis Biomarkers to Accelerate ADC Development
2:30 pm
- Quantifying tumor fibrosis to optimize ADC patient selection and stratification to improve response rates
- Measuring dynamic tumor extracellular matrix remodeling to capture proteolytic activities (cathepsins, metalloprotease etc.)
- Applying to ADC development through enhancing target engagement assessment, biomarker-driven trial design, and translational decision-making
- Linking extracellular matrix dynamics to payload delivery, target accessibility, and patient stratification and monitoring strategies
