Exploring Development of E7766-Based STING ADCs: Contextualizing Influence of Payload Linker Attachment Site & Cleavage Kinetics
- Delving into discovery of STING-agonist payload E7766, focusing on payload-linker attachment site
- Investigating linker cleavage rate to enhance in vitro and in vivo anti-tumor activities
- Showcasing in vitro and in vivo preclinical data of E7766- based STING ADCs