Presentation Preview: Evaluating Enzymatic Conjugation Strategies to Improve Dual Payload ADC Therapeutic Index at the Discovery Stage
- Employing innovative conjugation chemistry to deliver two distinct payloads to the antibody Fc region
- Optimizing conjugation process across DAR fine tuning and payload selection to reduce dual to enhance developability while accelerating candidate selection
- Showcasing impact of discovery-stage innovation to deliver ADC properties and differentiation potential to patients