Presentation Preview: Spotlighting Comprehensive Preclinical Development of Antifolate ADCs to Enter IND Phase for a Novel Drug-Linker Mechanism

  • Presenting development of a novel antifolate drug-linker platform, leveraging a toxin class with a clinically validated mechanism of action
  • Exploring in vitro and in vivo preclinical development and physicochemical properties of frontrunner antifolate ADC program
  • Laying out pharmacology studies and dose range finding investigation in the lead up to antifolate ADC IND studies