Spotlighting Challenges & Strategies for XDC Novel Conjugates (Dual Payload ADC & AOC) & Analytical Characterization

• Comparing conjugation designs for dual payload ADCs and AOCs, including single-site, dual-site, random, and site-specific approaches 
• Addressing early development challenges in hydrophobicity, conjugation precision, aggregation, and process control through linker design, reaction optimization, and purification
• Reviewing supporting analytical characterization and integrated CRDMO capabilities for advancing XDC programs toward GMP manufacturing

Speakers:

Huifang Dong

Head, LMP

Porton Chemicals