Greg Thurber
Professor of Chemical and Biomedical Engineering University of Michigan
Greg Thurber PhD. is a Professor of Chemical and Biomedical Engineering at the University of Michigan. The Thurber lab uses in vivo microscopy and mathematical simulations to develop quantitative and predictive simulations of drug and imaging agent distribution. The core theory is used in multiple applications, including pharmacokinetic and pharmacodynamic models for cancer therapy and chemoprevention and imaging agent development for screening, diagnosis, intraoperative imaging, and treatment monitoring. To this end, we are exploring a range of potential drug and imaging molecules, from small compounds to peptides, and all the way up to antibodies to better understand their targeting and distribution properties.
Seminars
- Leveraging understanding of ADC immune system interactions to unlock clinically relevant checkpoint inhibitor combinations
- What are other rationale-driven ADC combination partners in the immuneoncology field?
- Deep diving into preclinical Fc effect function to interpret role played in ADC combinations, contextualized with Fc silent versus wild type clinical readouts
