Greg Thurber

Greg Thurber

Company: University of Michigan

Job title: Associate Professor


Bystander Killing Potential in Antibody Drug Conjugate Design 12:00 pm

• Reflecting on recently approved ADCs against solid tumors that utilize bystander payloads (capable of killing adjacent cells) to target cancer cells in heterogeneous tumors • Payloads are often classified as bystander or non-bystander, but a range in bystander potential and payload tissue penetration determines the efficacy of released payload • Emphasizing that, similar to…Read more

day: day 2 track 2

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