Noemie Luong
Associate Principal Scientist, Translational Pharmacology Debiopharm
Seminars
Monday 12th October 2026
Evaluating Preclinical Performance of Novel Linker-Payloads to Widen ADC Therapeutic Index
12:00 pm
- Explaining the impact of ADC innovation to improve and widen therapeutic index and potentially maximize patient benefit
- Laying out MultiLINK novel linker-payload preclinical performance and mechanistic characterization to understand effect on tumor cells
- Contextualizing novel linker-payload preclinical proof-of-concept to enhance ADC tolerability and therapeutic index
Tuesday 13th October 2026
Leveraging MultiLINK™ Technology to Optimize ADC Selection & Improve the Therapeutic Window of ADCs
12:30 pm
- Maximizing therapeutic impact against low expressing targets and rapidly proliferating tumors using targeted high DAR ADC architectures
- Addressing current ADC challenges with novel linker-payloads: Preclinical proof-of-concept to preserve efficacy while enhancing ADC tolerability and therapeutic index
- Detailing novel linker mechanism for safer sequential release of MMAE
