Doug Kline
Senior Scientist Abbvie
Seminars
Monday 12th October 2026
Assessing Immunogenic Senescence to Promote the Activity of Topo1 Inhibitor ADCs
2:00 pm
- Exploring how Topo1 and Topo1 ADCs elicit immunogenic cell stress in vivo through the induction of cellular senescence
- Delineating the host immune cell requirements for Topo1-induced immunogenicity
- Identifying biomarkers of immunogenic cell stress mediated by Topo1 ADCs
