Marc robillard
cso Tagworks Pharmaceuticals
Seminars
Wednesday 5th November 2025
Showcasing the INDEnabling Data of the First Click- Cleavable ADC TGW101 Targeting Non-Internalizing TAG-72
2:30 pm
- Exploring design of TGW101 against TAG-72, cleaved in the extracellular TME by a Click-to-Release reaction
- Discussing TGW101 MOA, preclinical efficacy and safety data leading to a Phase I trial
- Linking TGW101 safety profile to PK and superior control of payload release, and how Click-to-Release expands ADC scope to non-internalizing targets while maximizing bystander effect
