Simon JIANG
Dr Lide Biotech
Seminars
Tuesday 4th November 2025
Evaluating a Translational Approach to ADCs: From In Vitro Organoids to Advanced In Vivo Models
2:30 pm
- Exploring the assessment of ADC efficacy through single-mouse in vitro PDXO, MiniPDX, PDX, and clinical MiniPDX models
- Demonstrating how models bridge preclinical findings to clinical indications, offering insights into drug efficacy and resistance mechanisms
- Highlighting the integration of diverse models to accelerate ADC development and guide decision-making in pharmaceutical R&D
