Explore the Agenda
Attendees can attend 1 morning workshop and 1 afternoon workshop.
8:00 am Check In, Morning Coffee & Light Refreshments
Workshops Designed for Beginners in the ADC Field
Deep-Diving into ADC Chemistry & Conjugation to Understand the Fundamentals Behind Next-Gen ADC Properties & Design
Understanding the challenges, opportunities and challenges at the forefront of ADC conjugation is vital to optimize ADC design and DAR capabilities from the get-go.
Join this workshop session to secure your understanding of fundamental principles of ADC conjugation, assess the pros and cons of next generation site-specific technologies and explore how conjugation design can lead to clinical differentiation
Workshop highlights include:
- Delving into ADC bioconjugation – what is the chemistry behind building ADCs?
- Assessing the pros and cons of different conjugation methods across site-specific and click chemistries, including biorthogonal methods
- Breaking down the foresight and innovation during discovery to maximize ADC differentiation in the clinic
Workshops Designed for Everyone in the ADC Field
Connecting ADC Design to Performance: How is Each Component Contributing to ADC Clinical Safety & Efficacy?
As more and more ADCs containing different payloads and linkers are being developed to tackle different targets, understanding their design becomes crucial to set up your therapy for success. In particular, how different designs and synergistic components play through to clinic development.
Join this workshop to contextualize the performance of different ADC designs and understand what makes a clinically effective ADC.
Workshop highlights include:
- Accurately characterizing antibody, linker, payload, and overall conjugate contributions to ADC clinical performance
- Contrasting different clinical profiles of ADCs differing in only one design component
- Optimizing ADC design to pair the right payload with the right target
12:00 pm Lunch & Networking
Workshops Designed for Beginners in the ADC Field
1:00 pm ADC Target 101: Keeping Up to Date with Cutting-Edge Anti-Tumor Target Discovery & Validation
Maintaining awareness of the hottest anti-tumor targets is fundamental for anyone looking to expand their ADC pipeline and innovation.
Join this workshop to unveil the desirable characteristics for ADC targets, discover the cutting-edge tools to probe cell surface tumor targets, and debate the risk vs. reward opportunities of going after first-in-class ADC development.
Workshop highlights include:
- Breaking down the desired characteristics for “clean” ADC targets and risk-benefit analysis for first-in-class therapeutics
- Exploring successes and challenges with emerging anti-tumor ADC targets
- Evaluating the opportunity of bispecific ADCs in target innovation
- Leveraging bioinformatics and omics technologies to screen and identify novel ADC targets
Workshops Designed for Everyone in the ADC Field
1:00 pm Navigating, Characterizing & Optimizing the ADC Clinical Development Journey Across Phases
With more ADCs enter the clinic than ever before, it has never been more important to optimize clinical strategy to be able to demonstrate differentiation and benefit to oncology patients.
Join this session to follow the journey of ADC clinical development from early to late-stage, spanning dose escalation, technologies and strategy for patient selection, and staying relevant in crowded target indications.
Workshop highlights include:
- Breaking down case studies of progressing ADC development across Phase I-III clinical trails
- Delving into exposure response modeling and analysis to inform ADC dosing and clinical activity
- Finding the right patient for the right ADC: evaluating when and how to implement patient cut-off criteria
Workshop leader to be announced