PRE-CONFERENCE SEMINAR DAY

Monday | November 4, 2024

8:30 am Check In, Morning Coffee & Refreshments

Introduction to ADCs

Introduction to ADCs

Chair: John Lambert, Independent Consultant & Honorary Professor, Queens University Belfast

           David Bramhill, President & Founder, Bramhill Biological Consulting

 

Are you new to the ADC field? If so, join our ADC 101 day to get your ADC knowledge up to scratch ahead of the scientific program days.

As more companies enter the ever-growing antibody-drug conjugate field, this seminar day will provide you with the critical knowledge gained over years of research and failed clinical trials that culminated in the presently approved ADCs and booming innovation in the field.

Led by long-standing experts & KOLs in the field, join this one-stop-shop of ADC learning to establish a core understanding of the essential elements in ADC discovery and early development.

Download the Full Event Guide for full details


09.30 am The morning session will cover:

  • Gaining familiarity with the fundamental early learnings that inform ADC design
  • Learning about the key insights that allowed early investigators to overcome the initial challenges
    that hindered early ADC program
  • Evaluating payload choices for ADCs
  • Reviewing linker design chemistry and what it can bring
  • Understanding the impact of conjugation site selection on ADCs

12.30 pm Lunch & Networking


1.30 pm The afternoon session will cover:

  • Gaining an understanding of the biological aspects of ADCs
  • Selecting the most appropriate ADC target
  • Choosing an optimum antibody format
  • Analyzing the choices and trade-offs in utilizing the chemistry ADC toolbox
  • Assessing key factors in the evaluation of efficacy information from in vivo preclinical models

2.30 pm Session Ends

2nd Novel Targeting Moiety & Payloads Day
5th Toxicity Day
2nd Biomarker & Patient Selection Day
8th ADCs in Combination Day
1st Pharmacology Day
3rd Bioanalytical & Process Analytical Day
6th CMC Day

2:30 pm Afternoon Break & Networking

3:15 pm Panel Session: Diversity & Inclusion in Oncology & ADC Clinical Trials

  • Radhika Balasubramani Director, Technical Product Steward, ADCs, Merck & Co
  • Adalynn Harris President & Chief Executive Officer, Equity Bridge
  • Ricki Fairley Chief Executive Officer & Co-Founder, TOUCH Black Breast Cancer Association
  • Mary Elmer Executive Director, Patient Engagement Oncology, Merck & Co

Synopsis

Ensuring diversity, inclusion, and a patient centric approach in clinical trials is crucial to encompass the broad range of lived experiences and diverse populations so that all patients can benefit from the fast-paced advances and innovations in ADC therapies. Attend this brand-new session led by oncology and patient advocates to explore the significance and importance of D&I in ADC development, learn from mistakes in the past, understand the patient perspective, and hear successful case studies of implementing patient considerations in clinical trial design and recruitment to ensure your ADC product development is representative to all patient populations. 

Register your interest when you sign up to attend the conference, then look out for an email to secure your spot! Highlights include:

  • Exploring the current status and opportunities for improvement in D&I throughout ADC product development – what mistakes have been made in the past?
  • Hearing case studies and company strategies to address and improve D&I in ADC clinical trials
  • Explaining the clinical trial design and recruitment considerations from the beginning to make ADC products representative to all patient populations
  • Breaking down takeaways of lived experience and incorporating learnings to help design ADC clinical trials

4:15 pm End of Pre-Conference Seminar Day

4:30 pm Evening Ambassador’s Reception

Hosted by Abzena

Synopsis

At the end of the pre-conference seminar, this invitation-only, informal evening reception is your perfect opportunity to reunite with old friends and meet new colleagues in the ADC field as the community returns to San Diego. Ahead of the main conference day, grab a drink of your choosing and network with the other attendees to strengthen and establish scientific and business relationships with your fellow innovators in the ADC field.

6:30 pm End of Ambassador’s Reception